I want to point you out to a very good game made by an italian independent game maker, Paolo Pedercini, who in turn is part of a small-but-very-famous indie reality called “la Molleindustria”.
La Molleindustria’s goal has always been to create games with a deeper theme than the average player would expect. They delved into unthinkable themes for videogames, like theology, religion, the role of the Pope, environment preservation and even pedo-pornography. Every time they did it with a strong and black humor, every time outputting though a game of great quality and, above all, of great meaning.
This game has been made by Paolo for a competition at TIGsource, and the theme was “art game”. This time the execution is a little bit more easy compared to their other games, but the end of the game is really bitter. Try it for yourself: